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Alloreactive (CD4-independent) CD8(+) T cells jeopardize long-term survival of intrahepatic islet allografts
Despite success of early islet allograft engraftment and survival in humans, late islet allograft loss has emerged as an important clinical problem. CD8(+) T cells that are independent of CD4(+) T cell help can damage allograft tissues and are resistant to conventional immunosuppressive therapies. P...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081659/ https://ncbi.nlm.nih.gov/pubmed/18522544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02219.x |
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