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Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1
Several signaling pathways including the Notch pathway can modulate Toll-like receptor (TLR) activation to achieve responses most appropriate for the environment. One mechanism of TLR-Notch crosstalk is TLR-induced expression of Notch ligands Jagged and Delta that feed back to engage Notch receptors...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010732/ https://ncbi.nlm.nih.gov/pubmed/20870935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001544 |
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