Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen

BACKGROUND AND PURPOSE: Recently, we identified etodolac as a possible ligand for the human intestinal proton-couple peptide transporter (hPEPT1). This raised the possibility that other non-steroidal anti-inflammatory drugs, and especially ibuprofen, could also interact with hPEPT1. Here, we have as...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Omkvist, Diana Højmark, Brodin, Birger, Nielsen, Carsten Uhd
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2010
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010583/
https://ncbi.nlm.nih.gov/pubmed/20726987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01000.x
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