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Molecular interactions between dipeptides, drugs and the human intestinal H(+)–oligopeptide cotransporter hPEPT1

The human intestinal proton-coupled oligopeptide transporter hPEPT1 has been implicated in the absorption of pharmacologically active compounds. We have investigated the interactions between a comprehensive selection of drugs, and wild-type and variant hPEPT1s expressed in Xenopus oocytes, using rad...

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Détails bibliographiques
Auteurs principaux: Sala-Rabanal, Monica, Loo, Donald D F, Hirayama, Bruce A, Turk, Eric, Wright, Ernest M
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817799/
https://ncbi.nlm.nih.gov/pubmed/16627568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107904
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