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A Quantitative Structure–Activity Relationship for Translocation of Tripeptides via the Human Proton-Coupled Peptide Transporter, hPEPT1 (SLC15A1)

The human intestinal proton-coupled peptide transporter, hPEPT1 (SLC15A1), has been identified as an absorptive transporter for both drug substances and prodrugs. An understanding of the prerequisites for transport has so far been obtained from models based on competition experiments. These models h...

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Detalhes bibliográficos
Main Authors: Omkvist, Diana Højmark, Larsen, Simon Birksø, Nielsen, Carsten Uhd, Steffansen, Bente, Olsen, Lars, Jørgensen, Flemming Steen, Brodin, Birger
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895456/
https://ncbi.nlm.nih.gov/pubmed/20449699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9195-z
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