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Japanese encephalitis virus induces matrix metalloproteinase-9 in rat brain astrocytes via NF-κB signalling dependent on MAPKs and reactive oxygen species

BACKGROUND AND PURPOSE: Japanese encephalitis virus (JEV) is a member of the family Flaviviridae and JEV infection is a major cause of acute encephalopathy in children, which destroys cells in the CNS, including astrocytes and neurons. However, the detailed mechanisms underlying the inflammatory act...

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Detalhes bibliográficos
Main Authors: Tung, Wei-Hsuan, Tsai, Hsin-Wen, Lee, I-Ta, Hsieh, Hsi-Lung, Chen, Wei-June, Chen, Yuh-Lien, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010568/
https://ncbi.nlm.nih.gov/pubmed/20698853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00982.x
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