Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

BACKGROUND: Transforming growth factor-β (TGF-β) and matrix metalloproteinases (MMPs) are the multifunctional factors during diverse physiological and pathological processes including development, wound healing, proliferation, and cancer metastasis. Both TGF-β and MMPs have been shown to play crucia...

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Autori principali: Hsieh, Hsi-Lung, Wang, Hui-Hsin, Wu, Wen-Bin, Chu, Po-Ju, Yang, Chuen-Mao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002339/
https://ncbi.nlm.nih.gov/pubmed/21134288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-88
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