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Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanisms

RAS GTPases control a major signaling network implicated in several cellular functions, including cell fate determination, proliferation, survival, differentiation, migration, and senescence. Within this network, signal flow through the RAF-MEK-ERK pathway, the first identified mitogen-associated pr...

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Bibliografiske detaljer
Main Authors: Tartaglia, Marco, Gelb, Bruce D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010252/
https://ncbi.nlm.nih.gov/pubmed/20958325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2010.05790.x
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