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RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it
In this issue of the JCI, Wu et al. and Marin et al. describe two new mouse models of inherited disorders of the RAS/MAPK signal transduction pathway that display hypertrophic cardiomyopathy (HCM); the model from the former paper was from a gain-of-function Raf1 mutation, and the model from the latt...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046639/ https://ncbi.nlm.nih.gov/pubmed/21339640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46399 |
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