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Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning

The up-regulation of α4β2* nicotinic acetylcholine receptors (nAChRs) by chronic nicotine is a cell-delimited process and may be necessary and sufficient for the initial events of nicotine dependence. Clinical literature documents an inverse relationship between a person’s history of tobacco use and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Srinivasan, Rahul, Pantoja, Rigo, Moss, Fraser J., Mackey, Elisha D.W., Son, Cagdas D., Miwa, Julie, Lester, Henry A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010053/
https://ncbi.nlm.nih.gov/pubmed/21187334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010532
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