Thrombin-dependent NF-κB Activation and Monocyte/Endothelial Adhesion Are Mediated by the CARMA3·Bcl10·MALT1 Signalosome

Thrombin is a potent modulator of endothelial function and, through stimulation of NF-κB, induces endothelial expression of intracellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). These cell surface adhesion molecules recruit inflammatory cells to the vessel wall a...

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Autori principali: Delekta, Phillip C., Apel, Ingrid J., Gu, Shufang, Siu, Katy, Hattori, Yoshiyuki, McAllister-Lucas, Linda M., Lucas, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009869/
https://ncbi.nlm.nih.gov/pubmed/21041303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158949
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