The CARMA3-Bcl10-MALT1 Signalosome Drives NF-κB Activation and Promotes Aggressiveness in Angiotensin II Receptor-positive Breast Cancer.

The angiotensin II receptor AGTR1, which mediates vasoconstrictive and inflammatory signaling in vascular disease, is overexpressed aberrantly in some breast cancers. In this study, we established the significance of an AGTR1-responsive NF-κB signaling pathway in this breast cancer subset. We docume...

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書誌詳細
出版年:Cancer Res
主要な著者: Ekambaram, Prasanna, Lee, Jia-Ying (Lloyd), Hubel, Nathaniel E., Hu, Dong, Yerneni, Saigopalakrishna, Campbell, Phil G., Pollock, Netanya, Klei, Linda R., Concel, Vincent J., Delekta, Phillip C., Chinnaiyan, Arul M., Tomlins, Scott A., Rhodes, Daniel R., Priedigkeit, Nolan, Lee, Adrian V., Oesterreich, Steffi, McAllister-Lucas, Linda M., Lucas, Peter C.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436094/
https://ncbi.nlm.nih.gov/pubmed/29259013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1089
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