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Aldosterone-sensitive repression of ENaCα transcription by a histone H3 lysine-79 methyltransferase

Aldosterone is a major regulator of epithelial Na(+) absorption. One of its principal targets is the epithelial Na(+) channel α-subunit (ENaCα), principally expressed in the kidney collecting duct, lung, and colon. Models of aldosterone-mediated trans-activation of the ENaCα gene have focused primar...

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Bibliografiske detaljer
Main Authors: Zhang, Wenzheng, Xia, Xuefeng, Jalal, Diana I., Kuncewicz, Teresa, Xu, William, Lesage, Gene D., Kone, Bruce C.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009459/
https://ncbi.nlm.nih.gov/pubmed/16236820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00431.2005
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