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Sp1 trans-activates and is required for maximal aldosterone induction of the αENaC gene in collecting duct cells
The epithelial Na(+) channel (ENaC) in the distal nephron constitutes the rate-limiting step for renal sodium reabsorption. Aldosterone increases tubular sodium absorption in large part by increasing αENaC transcription in collecting duct principal cells. We previously reported that Af9 binds to +78...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761204/ https://ncbi.nlm.nih.gov/pubmed/23804453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00177.2013 |
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