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B-raf Alternative Splicing Is Dispensable for Development but Required for Learning and Memory Associated with the Hippocampus in the Adult Mouse

The B-raf proto-oncogene exerts essential functions during development and adulthood. It is required for various processes, such as placental development, postnatal nervous system myelination and adult learning and memory. The mouse B-raf gene encodes several isoforms resulting from alternative spli...

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Detalhes bibliográficos
Main Authors: Valluet, Agathe, Hmitou, Isabelle, Davis, Sabrina, Druillennec, Sabine, Larcher, Magalie, Laroche, Serge, Eychène, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008692/
https://ncbi.nlm.nih.gov/pubmed/21203559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015272
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