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BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma
BACKGROUND: Although gene expression profile of multiple myeloma (MM) patients shows a wide range of Bik/Nbk expression, varying from absent to high, its regulation and function in myeloma cells is poorly understood. Thus, we addressed these questions in MM. METHODS: Human myeloma cell lines (HMCLs)...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008608/ https://ncbi.nlm.nih.gov/pubmed/21063407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605981 |
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