BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma

BACKGROUND: Although gene expression profile of multiple myeloma (MM) patients shows a wide range of Bik/Nbk expression, varying from absent to high, its regulation and function in myeloma cells is poorly understood. Thus, we addressed these questions in MM. METHODS: Human myeloma cell lines (HMCLs)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bodet, L, Ménoret, E, Descamps, G, Pellat-Deceunynck, C, Bataille, R, Le Gouill, S, Moreau, P, Amiot, M, Gomez-Bougie, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2010
Gaiak:
Translational Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008608/
https://ncbi.nlm.nih.gov/pubmed/21063407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605981
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