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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways

BACKGROUND: Human myeloma cell lines (HMCLs) are widely used for their representation of primary myeloma cells because they cover patient diversity, although not fully. Their genetic background is mostly undiscovered, and no comprehensive study has ever been conducted in order to reveal those detail...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Hematol Oncol
Κύριοι συγγραφείς: Tessoulin, Benoît, Moreau-Aubry, Agnès, Descamps, Géraldine, Gomez-Bougie, Patricia, Maïga, Sophie, Gaignard, Alban, Chiron, David, Ménoret, Emmanuelle, Le Gouill, Steven, Moreau, Philippe, Amiot, Martine, Pellat-Deceunynck, Catherine
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293660/
https://ncbi.nlm.nih.gov/pubmed/30545397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0679-0
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