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Proximity of the Start Codon to a Leaderless mRNA's 5′ Terminus Is a Strong Positive Determinant of Ribosome Binding and Expression in Escherichia coli

An AUG start codon is an important determinant of ribosome binding and expression of leaderless mRNAs in Escherichia coli. Using reporter constructs encoding mRNAs where the AUG start codon is preceded by untranslated leaders of various length and sequence, we find that close proximity of the start...

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Bibliografiske detaljer
Main Authors: Krishnan, Karthik M., Van Etten, William J., Janssen, Gary R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008523/
https://ncbi.nlm.nih.gov/pubmed/20971908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00756-10
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