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Proximity of the Start Codon to a Leaderless mRNA's 5′ Terminus Is a Strong Positive Determinant of Ribosome Binding and Expression in Escherichia coli

An AUG start codon is an important determinant of ribosome binding and expression of leaderless mRNAs in Escherichia coli. Using reporter constructs encoding mRNAs where the AUG start codon is preceded by untranslated leaders of various length and sequence, we find that close proximity of the start...

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Detalhes bibliográficos
Main Authors: Krishnan, Karthik M., Van Etten, William J., Janssen, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008523/
https://ncbi.nlm.nih.gov/pubmed/20971908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00756-10
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