Simvastatin Attenuates Astrogliosis after Traumatic Brain Injury through the Modulation of EGFR in Lipid Rafts

OBJECTIVE: Our previous studies demonstrated that simvastatin treatment promotes neuronal survival and reduces inflammatory cytokine release from astrocytes after traumatic brain injury (TBI) in rats. Since reactive astrocytes produce inflammation mediators, in the current study we investigated the...

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Hlavní autoři: Wu, Hongtao, Mahmood, Asim, Lu, Dunyue, Jiang, Hao, Xiong, Ye, Zhou, Dong, Chopp, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007601/
https://ncbi.nlm.nih.gov/pubmed/19895202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2009.9.JNS09859
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