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No Kiss1ng by leptin during puberty?

Leptin exerts a permissive action on puberty by stimulating release of gonadotropin-releasing hormone (GnRH) in the hypothalamus. However, GnRH neurons lack leptin receptor (LepR), indicating that leptin must indirectly regulate these neurons. The Kiss1 gene produces kisspeptins that stimulate GnRH...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Ahima, Rexford S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007174/
https://ncbi.nlm.nih.gov/pubmed/21183781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45813
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