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No Kiss1ng by leptin during puberty?
Leptin exerts a permissive action on puberty by stimulating release of gonadotropin-releasing hormone (GnRH) in the hypothalamus. However, GnRH neurons lack leptin receptor (LepR), indicating that leptin must indirectly regulate these neurons. The Kiss1 gene produces kisspeptins that stimulate GnRH...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3007174/ https://ncbi.nlm.nih.gov/pubmed/21183781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45813 |
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