Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

Granulocytes are pivotal regulators of tissue injury. However, the transcriptional mechanisms that regulate granulopoiesis under inflammatory conditions are poorly understood. Here we show that the transcriptional coregulator B cell leukemia/lymphoma 3 (Bcl3) limits granulopoiesis under emergency (i...

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Detalhes bibliográficos
Main Authors: Kreisel, Daniel, Sugimoto, Seiichiro, Tietjens, Jeremy, Zhu, Jihong, Yamamoto, Sumiharu, Krupnick, Alexander S., Carmody, Ruaidhri J., Gelman, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007142/
https://ncbi.nlm.nih.gov/pubmed/21157041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42596
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