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Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

Granulocytes are pivotal regulators of tissue injury. However, the transcriptional mechanisms that regulate granulopoiesis under inflammatory conditions are poorly understood. Here we show that the transcriptional coregulator B cell leukemia/lymphoma 3 (Bcl3) limits granulopoiesis under emergency (i...

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Detaylı Bibliyografya
Asıl Yazarlar: Kreisel, Daniel, Sugimoto, Seiichiro, Tietjens, Jeremy, Zhu, Jihong, Yamamoto, Sumiharu, Krupnick, Alexander S., Carmody, Ruaidhri J., Gelman, Andrew E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007142/
https://ncbi.nlm.nih.gov/pubmed/21157041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42596
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