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MAINTENANCE OF IKKβ ACTIVITY IS NECESSARY TO PROTECT LUNG GRAFTS FROM ACUTE INJURY
BACKGROUND: Signaling pathways that target I-κB kinase β (IKKβ) activation stimulate the expression of NF-κB-dependent genes and are thus thought to primarily promote inflammation and injury in solid organ grafts. METHODS: We examined the role of IKKβ in a mouse model of lung transplantation-mediate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020590/ https://ncbi.nlm.nih.gov/pubmed/21293322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31820ba2a0 |
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