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Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

Granulocytes are pivotal regulators of tissue injury. However, the transcriptional mechanisms that regulate granulopoiesis under inflammatory conditions are poorly understood. Here we show that the transcriptional coregulator B cell leukemia/lymphoma 3 (Bcl3) limits granulopoiesis under emergency (i...

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Hlavní autoři: Kreisel, Daniel, Sugimoto, Seiichiro, Tietjens, Jeremy, Zhu, Jihong, Yamamoto, Sumiharu, Krupnick, Alexander S., Carmody, Ruaidhri J., Gelman, Andrew E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007142/
https://ncbi.nlm.nih.gov/pubmed/21157041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42596
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