PS1-10: Response to Metformin and Genetic Variants of Organic Cation and Multidrug and Toxin Extrusion Transporters

Background and Aims: Metformin is the most widely-used anti-diabetic drug in the United States. However, medication management fails to achieve therapeutic goals in ~20% of patients. This study attempted to identify genetic polymorphisms associated with metformin treatment failure. We studied the as...

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Autors principals: Davis, Robert, Giacomini, Kathleen, Yee, Sook Wah, Jenkins, Gerard, McCarty, Catherine, Wilke, Russell
Format: Artigo
Idioma:Inglês
Publicat: Marshfield Clinic 2010
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SELECTED ABSTRACTS - HMORN 2010: Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006596/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3121/cmr.2010.943.ps1-10
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