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Differential induction of CD38 expression by TNF-α in asthmatic airway smooth muscle cells
The ADP-ribosyl cyclase activity of CD38, a membrane protein expressed in human airway smooth muscle (ASM) cells, generates cyclic ADP-ribose (cADPR), a Ca(2+)-mobilizing agent. cADPR-mediated Ca(2+) responses to agonists are augmented in human ASM cells by TNF-α. CD38-deficient mice fail to develop...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006261/ https://ncbi.nlm.nih.gov/pubmed/20693316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00021.2010 |
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