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Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone

BACKGROUND: CD38 is expressed in human airway smooth muscle (HASM) cells, regulates intracellular calcium, and its expression is augmented by tumor necrosis factor alpha (TNF-α). CD38 has a role in airway hyperresponsiveness, a hallmark of asthma, since deficient mice develop attenuated airway hyper...

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主要な著者: Tirumurugaan, Krishnaswamy G, Kang, Bit Na, Panettieri, Reynold A, Foster, Douglas N, Walseth, Timothy F, Kannan, Mathur S
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278140/
https://ncbi.nlm.nih.gov/pubmed/18341691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-26
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