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CD38 and Airway hyperresponsiveness: Studies on human airway smooth muscle cells and mouse models

Asthma is an inflammatory disease in which altered calcium regulation, contractility and airway smooth muscle (ASM) proliferation contribute to airway hyperresponsiveness and airway wall remodeling. The enzymatic activity of CD38, a cell-surface protein expressed in human ASM cells, generates calciu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Can J Physiol Pharmacol
Hauptverfasser: Guedes, Alonso GP, Deshpande, Deepak A, Dileepan, Mythili, Walseth, Timothy F, Panettieri, Reynold A, Subramanian, Subbaya, Kannan, Mathur S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648235/
https://ncbi.nlm.nih.gov/pubmed/25594684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2014-0410
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