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Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype
CD38 is a transmembrane glycoprotein expressed in airway smooth muscle cells. The enzymatic activity of CD38 generates cyclic ADP-ribose from β-NAD. Cyclic ADP-ribose mobilizes intracellular calcium during activation of airway smooth muscle cells by G-protein-coupled receptors through activation of...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Publishing Corporation
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508580/ https://ncbi.nlm.nih.gov/pubmed/23213344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/289468 |
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