Rewiring of Genetic Networks in Response to DNA Damage

Although cellular behaviors are dynamic, the networks that govern these behaviors have been mapped primarily as static snapshots. Using an approach called differential epistasis mapping, we have discovered widespread changes in genetic interaction among yeast kinases, phosphatases, and transcription...

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Autores principales: Bandyopadhyay, Sourav, Mehta, Monika, Kuo, Dwight, Sung, Min-Kyung, Chuang, Ryan, Jaehnig, Eric J., Bodenmiller, Bernd, Licon, Katherine, Copeland, Wilbert, Shales, Michael, Fiedler, Dorothea, Dutkowski, Janusz, Guénolé, Aude, van Attikum, Haico, Shokat, Kevan M., Kolodner, Richard D., Huh, Won-Ki, Aebersold, Ruedi, Keogh, Michael-Christopher, Krogan, Nevan J., Ideker, Trey
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006187/
https://ncbi.nlm.nih.gov/pubmed/21127252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1195618
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