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A multilevel model to address batch effects in copy number estimation using SNP arrays
Submicroscopic changes in chromosomal DNA copy number dosage are common and have been implicated in many heritable diseases and cancers. Recent high-throughput technologies have a resolution that permits the detection of segmental changes in DNA copy number that span thousands of base pairs in the g...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006124/ https://ncbi.nlm.nih.gov/pubmed/20625178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq043 |
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