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Estimating Genome-Wide Copy Number Using Allele-Specific Mixture Models

Genomic changes such as copy number alterations are one of the major underlying causes of human phenotypic variation among normal and disease subjects. Array comparative genomic hybridization (CGH) technology was developed to detect copy number changes in a high-throughput fashion. However, this tec...

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Detalhes bibliográficos
Main Authors: Wang, Wenyi, Carvalho, Benilton, Miller, Nathaniel D., Pevsner, Jonathan, Chakravarti, Aravinda, Irizarry, Rafael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612042/
https://ncbi.nlm.nih.gov/pubmed/18707534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2007.0148
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