Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays

Multiple algorithms have been developed for the purpose of calling single nucleotide polymorphisms (SNPs) from Affymetrix microarrays. We extend and validate the algorithm CRLMM, which incorporates HapMap information within an empirical Bayes framework. We find CRLMM to be more accurate than the Aff...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Shin, Carvalho, Benilton, Cutler, David J, Arking, Dan E, Chakravarti, Aravinda, Irizarry, Rafael A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643934/
https://ncbi.nlm.nih.gov/pubmed/18387188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r63
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