Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays

Multiple algorithms have been developed for the purpose of calling single nucleotide polymorphisms (SNPs) from Affymetrix microarrays. We extend and validate the algorithm CRLMM, which incorporates HapMap information within an empirical Bayes framework. We find CRLMM to be more accurate than the Aff...

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Bibliografiske detaljer
Main Authors: Lin, Shin, Carvalho, Benilton, Cutler, David J, Arking, Dan E, Chakravarti, Aravinda, Irizarry, Rafael A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643934/
https://ncbi.nlm.nih.gov/pubmed/18387188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r63
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