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Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays
Multiple algorithms have been developed for the purpose of calling single nucleotide polymorphisms (SNPs) from Affymetrix microarrays. We extend and validate the algorithm CRLMM, which incorporates HapMap information within an empirical Bayes framework. We find CRLMM to be more accurate than the Aff...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643934/ https://ncbi.nlm.nih.gov/pubmed/18387188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r63 |
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