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Molecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assembly
Frataxin, a conserved nuclear encoded mitochondrial protein, plays a direct role in iron-sulfur cluster biosynthesis within the ISC assembly pathway. Humans with frataxin deficiency have Friedreich’s ataxia, a neurodegenerative disorder characterized by mitochondrial iron overload and disruption in...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3005940/ https://ncbi.nlm.nih.gov/pubmed/20815377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1008613 |
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