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Frataxin and Mitochondrial FeS Cluster Biogenesis
Friedreich ataxia is an inherited neurodegenerative disease caused by frataxin deficiency. Frataxin is a conserved mitochondrial protein that plays a role in FeS cluster assembly in mitochondria. FeS clusters are modular cofactors that perform essential functions throughout the cell. They are synthe...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930671/ https://ncbi.nlm.nih.gov/pubmed/20522547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.118679 |
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