Frataxin and Mitochondrial FeS Cluster Biogenesis

Friedreich ataxia is an inherited neurodegenerative disease caused by frataxin deficiency. Frataxin is a conserved mitochondrial protein that plays a role in FeS cluster assembly in mitochondria. FeS clusters are modular cofactors that perform essential functions throughout the cell. They are synthe...

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Bibliographic Details
Main Authors: Stemmler, Timothy L., Lesuisse, Emmanuel, Pain, Debkumar, Dancis, Andrew
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930671/
https://ncbi.nlm.nih.gov/pubmed/20522547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R110.118679
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