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Molecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assembly
Frataxin, a conserved nuclear encoded mitochondrial protein, plays a direct role in iron-sulfur cluster biosynthesis within the ISC assembly pathway. Humans with frataxin deficiency have Friedreich’s ataxia, a neurodegenerative disorder characterized by mitochondrial iron overload and disruption in...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3005940/ https://ncbi.nlm.nih.gov/pubmed/20815377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1008613 |
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