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Mutation in the Fe–S scaffold protein Isu bypasses frataxin deletion

Frataxin is a conserved mitochondrial protein deficient in patients with Friedreich’s ataxia. Frataxin has been implicated in control of iron homoeostasis and Fe–S cluster assembly. In yeast or human mitochondria, frataxin interacts with components of the Fe–S cluster synthesis machinery, including...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoon, Heeyong, Golla, Ramesh, Lesuisse, Emmanuel, Pain, Jayashree, Donald, Jason E., Lyver, Elise R., Pain, Debkumar, Dancis, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018837/
https://ncbi.nlm.nih.gov/pubmed/21936771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111637
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