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Mutation in the Fe–S scaffold protein Isu bypasses frataxin deletion

Frataxin is a conserved mitochondrial protein deficient in patients with Friedreich’s ataxia. Frataxin has been implicated in control of iron homoeostasis and Fe–S cluster assembly. In yeast or human mitochondria, frataxin interacts with components of the Fe–S cluster synthesis machinery, including...

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Bibliografische gegevens
Hoofdauteurs: Yoon, Heeyong, Golla, Ramesh, Lesuisse, Emmanuel, Pain, Jayashree, Donald, Jason E., Lyver, Elise R., Pain, Debkumar, Dancis, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018837/
https://ncbi.nlm.nih.gov/pubmed/21936771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111637
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