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Mutation in the Fe–S scaffold protein Isu bypasses frataxin deletion
Frataxin is a conserved mitochondrial protein deficient in patients with Friedreich’s ataxia. Frataxin has been implicated in control of iron homoeostasis and Fe–S cluster assembly. In yeast or human mitochondria, frataxin interacts with components of the Fe–S cluster synthesis machinery, including...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018837/ https://ncbi.nlm.nih.gov/pubmed/21936771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111637 |
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