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Identification of a Nfs1p-bound persulfide intermediate in Fe-S cluster synthesis by intact mitochondria

Cysteine desulfurases generate a covalent persulfide intermediate from cysteine, and this activated form of sulfur is essential for the synthesis of iron-sulfur (Fe-S) clusters. In yeast mitochondria, there is a complete machinery for Fe-S cluster synthesis, including a cysteine desulfurase, Nfs1p....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pandey, Alok, Yoon, Heeyong, Lyver, Elise R., Dancis, Andrew, Pain, Debkumar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462219/
https://ncbi.nlm.nih.gov/pubmed/22813754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2012.07.103
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