Isd11p Protein Activates the Mitochondrial Cysteine Desulfurase Nfs1p Protein

Cysteine desulfurases perform pyridoxal phosphate (PLP)-dependent desulfuration of cysteine. The key steps of the enzymatic cycle include substrate binding to PLP, formation of a covalent persulfide intermediate at the active site cysteine, and transfer of sulfur to recipients for use in various met...

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Bibliografiske detaljer
Main Authors: Pandey, Alok, Yoon, Heeyong, Lyver, Elise R., Dancis, Andrew, Pain, Debkumar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207418/
https://ncbi.nlm.nih.gov/pubmed/21908622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.288522
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