A Major Role for hERG in Determining Frequency of Reentry in Neonatal Rat Ventricular Myocyte Monolayer

RATIONALE: The rapid delayed rectifier potassium current, I(Kr), which flows through the human ether-a-go-go-related (hERG) channel is a major determinant of the shape and duration of the human cardiac action potential (APD). However, it is unknown whether the time dependency of I(Kr) enables it to...

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Autori principali: Hou, Luqia, Deo, Makarand, Furspan, Philip, Pandit, Sandeep V., Mironov, Sergey, Auerbach, David S, Gong, Qiuming, Zhou, Zhengfeng, Berenfeld, Omer, Jalife, José
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005848/
https://ncbi.nlm.nih.gov/pubmed/20947828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.232470
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