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Asymmetric Allosteric Signaling in Aspartate Transcarbamoylase

Here we use the fluorescence from a genetically encoded unnatural amino acid, L-(7-hydroxycoumarin-4-yl)ethylglycine (HCE-Gly) replacing an amino acid in the regulatory site of Escherichia coli aspartate transcarbamoylase (ATCase) to decipher the molecular details of regulation of this allosteric en...

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Main Authors: Mendes, Kimberly R., Martinez, Jessica A., Kantrowitz, Evan R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004224/
https://ncbi.nlm.nih.gov/pubmed/20210358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9003207
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