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Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase
E. coli aspartate transcarbamoylase (ATCase) allosterically regulates pyrimidine nucleotide biosynthesis. The enzyme is inhibited by CTP and can be further inhibited by UTP, although UTP alone has little or no influence on activity; however, the mechanism for the synergistic inhibition is still unkn...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461825/ https://ncbi.nlm.nih.gov/pubmed/22906065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300920m |
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