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DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps

The assembly of the spliceosome involves dynamic rearrangements of interactions between snRNAs, protein components, and the pre-mRNA substrate. DExD/H-box ATPases are required to mediate structural changes of the spliceosome, utilizing the energy of ATP hydrolysis. Two DExD/H-box ATPases are require...

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Autori principali: Tseng, Chi-Kang, Liu, Hsueh-Lien, Cheng, Soo-Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004056/
https://ncbi.nlm.nih.gov/pubmed/21098140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2459611
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