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Initial Testing of the Replication Competent Seneca Valley Virus (NTX-010) by the Pediatric Preclinical Testing Program

BACKGROUND: Seneca Valley virus (NTX-010) is a non-recombinant, replication competent RNA virus that is undergoing phase 1 clinical trials in adults for tumors with neuroendocrine characteristics. Here we have evaluated the antitumor activity of NTX-010 administered systemically. PROCEDURES: In vitr...

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主要な著者: Morton, Christopher L., Houghton, Peter J., Kolb, E. Anders, Gorlick, Richard, Reynolds, C. Patrick, Kang, Min H., Maris, John M., Keir, Stephen T., Wu, Jianrong, Smith, Malcolm A.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003870/
https://ncbi.nlm.nih.gov/pubmed/20582972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22535
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