Pathology tissue–chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

Epigenetic alterations in the pattern of DNA and histone modifications play a crucial role in cancer development. Analysis of patient samples, however, is hampered by technical limitations in the study of chromatin structure from pathology archives that usually consist of heavily fixed, paraffin-emb...

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Detaylı Bibliyografya
Asıl Yazarlar: Fanelli, Mirco, Amatori, Stefano, Barozzi, Iros, Soncini, Matias, Dal Zuffo, Roberto, Bucci, Gabriele, Capra, Maria, Quarto, Micaela, Dellino, Gaetano Ivan, Mercurio, Ciro, Alcalay, Myriam, Viale, Giuseppe, Pelicci, Pier Giuseppe, Minucci, Saverio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003125/
https://ncbi.nlm.nih.gov/pubmed/21106756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007647107
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