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Pathology tissue–chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples

Epigenetic alterations in the pattern of DNA and histone modifications play a crucial role in cancer development. Analysis of patient samples, however, is hampered by technical limitations in the study of chromatin structure from pathology archives that usually consist of heavily fixed, paraffin-emb...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fanelli, Mirco, Amatori, Stefano, Barozzi, Iros, Soncini, Matias, Dal Zuffo, Roberto, Bucci, Gabriele, Capra, Maria, Quarto, Micaela, Dellino, Gaetano Ivan, Mercurio, Ciro, Alcalay, Myriam, Viale, Giuseppe, Pelicci, Pier Giuseppe, Minucci, Saverio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003125/
https://ncbi.nlm.nih.gov/pubmed/21106756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007647107
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